Aumentar el consumo de salmón durante el embarazo no incrementa el estrés oxidativo

Título: Does Increased Intake of Salmon Increase Markers of Oxidative Stress in Pregnant Women? The Salmon in Pregnancy Study

Resumen: The Salmon in Pregnancy Study provided two meals of salmon per week to pregnant women from week 20 of gestation; the control group maintained their habitual diet low in oily fish. Salmon is a rich source of marine n-3 fatty acids. Since marine n-3 fatty acids may increase oxidative stress, we investigated whether increased salmon consumption could affect markers of oxidative stress in mid and late pregnancy. Urinary 8-iso-prostaglandin F(2 alpha), urinary 8-hydroxy-2'-deoxyguanosine, and plasma lipid peroxide concentrations did not change from week 20 to 38 of pregnancy and were not altered by increased consumption of salmon. Thus, increased intake of salmon during pregnancy does not increase oxidative stress, as judged by the markers of oxidative damage to lipids and DNA measured herein

Autores: Cruz E.Garcia-Rodriguez, Johanna Helmersson-Karlqvist, Maria Dolores Elizabeth Miles, Paul Noakes, Maria Vlachava, Lefkothea-Stella Kremmyda, Norma D. Diaper, Keith M.Godfrey, Philip C. Calder, Angel Gil, Samar Basu.

Direcciones:

1. Univ Auvergne, Lab Biochem Mol Biol & Nutr, EA Nutr Cancerogenesis & Antitumor Therapy 4233, F-63001 Clermont Ferrand, France

2. Uppsala Univ, Dept Publ Hlth & Caring Sci, Fac Med, Uppsala, Sweden

3. Univ Uppsala Hosp, Ctr Excellence Inflammat, Uppsala, Sweden

4. Univ Granada, Dept Biochem & Mol Biol 2, Biomed Res Ctr, Inst Nutr & Food Technol Jose Mataix, Granada, Spain

5. Univ Uppsala Hosp, Dept Med Sci, Uppsala, Sweden

6. Univ Southampton, Dev Origins Hlth & Dis Div, Sch Med, Southampton, Hants, England

7. Univ Southampton, Southampton Med Res Council, Lifecourse Epidemiol Unit, Southampton, Hants, England

8. Southampton Univ Hosp NHS Trust, Southampton NIHR Nutr Diet & Lifestyle Biomed Res, Southampton, Hants, England